Serine Amino Acid Benefits

amino acids serine

Serine is the amino acid with an uncharged polar side chain. It was isolated first from the silk protein named sericin in 1865. It is a non-essential amino acid since it is synthesized in our body. It has six codon which is AGU, AGC, UCC, UCU, UGC, and UCA. It is they hydrophilic amino acid because of hydrogen bonding capacity. It has L- isomer form which is the only form of serine that takes part in the protein synthesis.

Sources of Serine: Some of its sources are as follow.

Animal origin sources: These include meat, beef, dairy products like cheese etc.

Plant origin sources: These include peanuts, wheat, gluten, and soy products.

Biosynthesis

In our body serine is formed from glycine amino acid. Glycine is converted into serine by the addition of hydroxymethyl group and this reaction is catalyzed by serine hydroxymethyl transferase enzymes which also requires the two coenzymes namely, tetrahydrofolate, and pyridoxal phosphate.

Physiological Functions

  • Serine is used in the synthesis of cysteine, cephalins, and choline.
  • It is utilized in the synthesis of purines and pyrimidines which further produce DNA and RNA.
  • Serine can also give rise to pyruvate and glycine.
  • Glycine is formed by the reversal of serine hydroxymethyl transferase reactions.
  • Pyruvate is produced when serine reacts with water in the presence of serine dehydratase enzyme.
  • Serine has also been found the precursor of sphingolipids and folate. These two acts as a donor of one carbon atom in biosynthesis.
  • It takes part in the muscle formation as well as in the maintenance of a normal immune system.
  • Serine is also utilized in the synthesis of tryptophan amino acid which then gives rise to important neurotransmitter the serotonin in the central nervous system. Their deficiency leads to depression, irritability, insomnia, anxiety, and confusion.
  • Serine has also been found in the component of brain proteins and nerve coverings. In the case of its deficiency, myelin sheath becomes less efficient in performing their normal functions. So serine has been found very important for our brain.
  • In skin moisturizing creams, serine is also one of the constituents.
  • It performs an important function in the catalytic role of numerous enzymes, for example, it has been found to occur in the active sites of trypsin, chymotrypsin, and various other enzymes.
  • Because of the presence of hydroxyl group in it, serine acts as a carrier of phosphoric acid in phosphoproteins.
  • Serine has found to increase the absorption of creatine. Creatine is important for muscles as it makes them strong and increases their mass.
  • It has been found that serine plays a role in the production of antibodies.
  • An enzyme called serine protease has been found to acts as a clotting factor as well as beneficial in blood coagulation disorders.

Serine supplements have been found useful for our body. For better results, they can be taken with folic acid, niacin and vitamin B6 because these vitamins enhance its formation.

Related posts:

Amino acids for brain: DL-Phenylalanine ...
There are 300 naturally occurring amino acids (AA) but only twenty take parts in the formation of proteins, plant as well as the animal in origin. Th...
Lysine Amino Acid Benefits
Lysine is the amino acid with the basic side chain. It is an essential amino acid as it is not manufactured in our body so it needs to be supplied fr...
Tryptophan Amino Acid Benefits
Tryptophan amino acid is the essential amino acid. This means it must be provided through food to the body. It is one of the amino acids which in its...
Cysteine Amino Acid Benefits
Cysteine is an uncharged amino acid with polar side chain and hydrophobic in nature. It is sulfur-containing amino acid and S atom in cysteine is its...
Boost your "Feel Good" neurons...
What would you say if I would tell you that your happiness is right there in your brain...but you can't feel it because of all the other bad feelings ...
Amino acid supplements good for your bra...
The human brain is a marvel of nature. It is more complex than any machine man has ever made. It performs tasks that seem impossibly difficult and ach...