Its chemical names are 5′-adenylic acid, ergadenylic acid, and adenosine monophosphate. This vitamin is soluble in water. It is synthesized in our body as well along with its wide distribution in the nature. It is one of the nucleoside present in the RNA. It contains sugar ribose as well as phosphate group.
It is present in animal sources as well as in plant sources.
- Animal Sources: Yeast especially Brewer’s yeast, yogurt, egg beef liver, cheese pig’s kidney, and milk, are its animal sources.
- Plant Sources: Oatmeal, whites, nuts like hazelnuts, walnuts and almonds are rich in vitamin B8. Mushrooms, rice germ, wheat germ, whole meal bread, peanut butter and rice bran also contain this vitamin.
- It is produced when ATP is manufactured in our body by the action of enzyme adenylase kinase. Two ADP linked together to form ATP and this AMP (adenosine monophosphate)
- It can also be formed from the hydrolysis of adenosine diphosphate. Adenosine triphosphate can also give rise to AMP.
- AMP in the form of cyclic AMP is very important as it acts as a second messenger system and is essential for regulated intracellular signals. It may convert into ATP by the enzyme action adenylase cyclase and this is regulated by glucagon or adrenaline hormones.
- It is necessary for the synthesis of ADP, ATP and RNA.
- It plays role in our immune system
- Vitamin B8 causes promotion of functional nervous system
- It is also important for our nails as well as skin. It prevents the premature graying of hair among young or adults.
- It may also be found helpful in RBC’s production.
- This vitamin is also effectively utilized in the treatment of some psychological disorders like Obsessive Compulsive Disorder, bulimia, mood disorders, depression, panic attacks, and the anxiety etc.
- Vitamin B8 also provides relief if patient is suffering from of diabetic neuropathy.
- It has been believed by some expert that vitamin B8 stops insomnia in people suffering from it.
- This vitamin deficiency leads to low synthesis of ADP, ATP and RNA in the body.
- There occurs inhibition in the breakdown of food in order to produce energy.
- Its deficiency results in reduction in hormonal function.
- Weak muscles, lack of appetite, muscle cramps, fatigue, generalized body aches, hair loss and pricking sensation in the skin may be felt by the patient.
- Premature graying of hair, seborrhea and dandruff also occur
- Eczema and anemia is also found among this vitamin deficient people
- There may arise heart diseases and the lung diseases also in case of its very severe deficiency.
- Nervous system abnormalities manifest as tingling in hands and feet, drowsiness, confusion, lethargy and hallucination are also due vitamin B8 deficiency.
It has been claimed by researches this substance is actually an essential vitamin for our body.
Vitamin B8 if taken in excessive amount leads to toxicity which involves confusion, hallucination, lethargy and gastrointestinal problems such as nausea, vomiting etc. The daily recommended dose for Vitamin B8 is almost about 400 µgrams.