Pyrrolysine Amino Acid Benefits

amino acids pyrrolysine

Pyrrolysine is the largest amino acid known which is naturally occurring. It is encoded genetically by a nucleotide sequence that usually halts the translation of mRNA.

It is found in bacterium and in few species of Archaea. It is just like the lysine but it is different in having pyrrole ring which is attached to the one end of the lysine amino acid.

Biosynthesis

In our body pyrrolysine is produced by special transfer RNA and an enzyme called aminoacyl transfer RNA. This amino acid also forms a part of genetic code.

Functions

In our body it is incorporated into active sites of many enzymes for example methyltransferase. Here on this enzyme is rotated freely. It is incorporated during the process of translation in to messenger RNA with the help of codon UAG. This amino acid has not been studies too much. There are not many known functions of it.

Structure

It contains three chiral centers which results in eight enantiomers, but only one of these is utilized. Pyrrolysine is a labile amino acid and it can easily be destroyed by heat and acid hydrolysis. This amino acid was also found to be involved in the methanogenesis. The methane today is the green house gas which is quite powerful. Pyrrolysine is the twenty second amino acid of proteinogenic type.

Related posts:

Amino acids for brain: DL-Phenylalanine ...
There are 300 naturally occurring amino acids (AA) but only twenty take parts in the formation of proteins, plant as well as animal in origin. They ...
Isoleucine Amino Acid Benefits
Isoleucine is an essential amino acid so it needs to be provided by the food to our body. It has aliphatic side chain and is non polar. It is also h...
Phenylalanine Amino Acid Benefits
Phenylalanine is the amino acid with the aromatic side chain and is relatively polar.  It is one of the essential amino acid which means it...
Threonine Amino Acid Benefits
Threonine is the uncharged polar amino acid. It is an essential amino acid as it is not manufactured in our body. It must be provided through food t...
Tryptophan Amino Acid Benefits
Tryptophan amino acid is the essential amino acid. This means it must be provided through food to the body. It is one of the amino acid which in its...
Glutamic Amino Acid Benefits
Glutamic acid is an amino acid with acidic side chain and negative charge at neutral pH. It is non essential amino acid as it is synthesized in the ...